• Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder 

      McCarthy, Michael J.; Stautland, Andrea; Jakobsen, Petter; Ødegaard, Ketil Joachim; Andreassen, Ole Andreas; Djurovic, Srdjan; Morken, Gunnar; Schøyen, Helle Kristine; McInnis, Melvin G.; Alda, Martin; Gage, Fred H.; Calabrese, Joseph R.; Zandi, Peter P.; Nievergelt, Caroline M.; Shilling, Paul D.; Kelsoe, John R. (Journal article; Peer reviewed, 2018)
      Bipolar disorder (BD) is a serious mood disorder associated with circadian rhythm abnormalities. Risk for BD is genetically encoded and overlaps with systems that maintain circadian rhythms. Lithium is an effective mood ...
    • Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis 

      Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Peer reviewed; Journal article, 2023)
      Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...
    • The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample 

      Ødegaard, Ketil Joachim; Alda, Martin; Anand, Anit; Andreassen, Ole Andreas; Balaraman, Yokesh; Berrettini, Wade H.; Bhattacharjee, Abesh; Brennand, Kristen J.; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Claasen, Ana; Coryell, William H.; Craig, David; DeModena, Anna; Frye, Mark A.; Gage, Fred H.; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G.; McCarthy, Michael J.; McInnis, Melvin G.; Maihofer, Adam X.; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Pham, Son; Schøyen, Helle Kristine; Shekhtman, Tatyana; Shilling, Paul D.; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2016)
      Background Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The cornerstone of clinical management is stabilization ...
    • The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample 

      Ødegaard, Ketil Joachim; Alda, Martin; Anand, Anit; Andreassen, Ole Andreas; Balaraman, Yokesh; Berrettini, Wade H.; Bhattacharjee, Abesh; Brennand, Kristen J.; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Claasen, Ana; Coryell, William H.; Craig, David; DeModena, Anna; Frye, Mark A.; Gage, Fred H.; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G.; McCarthy, Michael J.; McInnis, Melvin G.; Maihofer, Adam X.; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Pham, Son; Schoeyen, Helle K.; Shekhtman, Tatyana; Shilling, Paul D.; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2016)
      Background Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The cornerstone of clinical management is stabilization ...